Sanford Health is launching its second adipose-derived stem cell clinical trial – this one to focus on non-healing leg wounds. The trial, which opened in September with expanded criteria, is a phase 1 trial to study the safety and efficacy of using adipose … This Post Originally Appeared via Bing News
The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond! Lessons Learned from CAR T cell Therapies for B Cell Malignancies Soon to be approved chimeric antigen receptor T (CAR T) cell therapies for B cell malignancies in pediatric …
The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond! Enhanced Generation of Human Retinal Ganglion Cells A new report from the labs of Donald J. Zack (Johns Hopkins University School of Medicine, Maryland, USA) and Derek S. …
The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond! Naming MSCs – The Battle Goes on! A recent STEM CELLS Translational Medicine Perspective laid out the claim for mesenchymal stem cells (MSCs) to be renamed “medicinal signaling cells”, …
ViaCyte Inc., a privately held regenerative medicine company, has been awarded a $20 million grant from the California Institute for Regenerative Medicine (CIRM) to support the clinical development of its PEC-Direct™ product candidate. This novel cell replacement therapy is being developed as a functional cure for patients with type 1 diabetes who are at high …
It’s a Wonderful Life is a Christmas classic. In this movie, the main character gets in a rut and questions whether he should ever been born. He’s then met by a near do well angel who grants his wish and shows him a world where his town has gone to pot (or Potter). In …
The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond! ERCs Induce Cardiac Allograft Tolerance Studies have demonstrated the therapeutic potential of mesenchymal-like endometrial regenerative cells (ERCs) in various disease models, and now, new research from Hao Wang …
Review of “Immunomodulatory Effects of Adipose Stromal Vascular Fraction Cells Promote Alternative Activation Macrophages to Repair Tissue Damage” from STEM CELLS by Stuart P. Atkinson Autoimmune responses in the peripheral lymphoid tissues against the protein sheath that insulates nerve axons in the central nervous system (CNS) leads to the unfortunately common neurodegenerative disease Multiple Sclerosis …
Cliff et al. show that, contrary to prior understanding, a metabolic switch away from glycolysis is not a required step for human pluripotent stem cell differentiation, and that, in fact, differentiation to ectoderm requires maintenance of high glycolytic flux via MYC/MYCN activity, indicating its role as a developmental regulator. This Post Originally Appeared at Cell Stem …
The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond! Quality Control for iPSCs! Therapeutic applications for human induced pluripotent stem cells (hiPSC) require a means of first assessing hiPSC quality. Researchers from the lab of Timothy J. …
There are several different kinds of stem cells. Mesenchymal Stem Cells (MSCs) are found in bone marrow and fat tissue, and have the strongest potential to repair muscle, bone, joint and soft tissue injuries. These cells have the ability to self-replicate … This Post Originally Appeared via Bing News
The Stem Cells Portal brings you a roundup of some of the new and exciting stories in the ever-changing world of stem cells, regenerative medicine, and beyond! Unraveling Kidney Disease with hPSC-Podocytes A new study from the laboratories of Benjamin S. Freedman (University of Washington, Seattle, USA) and Kelly M. McNagny (University of British Columbia, …